منابع مشابه
Abnormal Early Cleavage Events Predict Early Embryo Demise: Sperm Oxidative Stress and Early Abnormal Cleavage
Human embryos resulting from abnormal early cleavage can result in aneuploidy and failure to develop normally to the blastocyst stage. The nature of paternal influence on early embryo development has not been directly demonstrated although many studies have suggested effects from spermatozoal chromatin packaging, DNA damage, centriolar and mitotic spindle integrity, and plasma membrane integrit...
متن کاملThe Pregnancy Outcomes of Day 2 versus Day 3 Embryo Transfer: A Cross-Sectional Study
Background The objective was to evaluate whether extending the embryo culture period from 2 to 3 days would yield a more optimal selection of viable embryos, thereby increasing the pregnancy rat. MaterialsAndMethods We have retrospectively analyzed pregnancy rates in the patients who had embryo transfer either on day 2 (582 patients) or on day 3 (387 patients) post-insemination over a 10-month ...
متن کاملThe cleavage stage embryo.
A precise embryo quality evaluation is of paramount importance to sustain a successful in vitro fertilization (IVF) program. In most IVF clinics around the world, this quality assessment relies mainly on the morphological evaluation of cleavage stage embryos. Embryologists should be able to correlate the features observed at the optical microscope with the implantation potential of each particu...
متن کاملI-38: Chromosome Instability in The Cleavage Stage Embryo
Recently, we demonstrated chromosome instability (CIN) in human cleavage stage embryogenesis following in vitro fertilization (IVF). CIN not necessarily undermines normal human development (i.e. when remaining normal diploid blastomeres develop the embryo proper), however it can spark a spectrum of conditions, including loss of conception, genetic disease and genetic variation development. To s...
متن کاملDay 3 embryo transfer with combined evaluation at the pronuclear and cleavage stages compares favourably with day 5 blastocyst transfer.
BACKGROUND The respective advantages of day 3 and day 5 embryo transfer are a matter of debate. Previous comparisons did not include pronuclear stage zygote scoring and cumulative success rates (fresh and cryopreserved embryos). METHODS Patients were randomized prospectively for day 3 or day 5 embryo transfer. Day 3 embryos were selected for transfer and cryopreservation by using combined eva...
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ژورنال
عنوان ژورنال: Reproductive BioMedicine Online
سال: 2007
ISSN: 1472-6483
DOI: 10.1016/s1472-6483(10)61062-0